SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74b45fa26d6e92855e672a6a2451ad503c8464cdfb9b68119aacdc6e1bb6cc40' 
  AND token = 'HZawkcfyS1in6uyH/++7jMaaSrq/JV8Wjwo1nYQGGTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}