SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43ec4f6176389a3d82b64a1d17e4b8b9e68a2e082a757a7e9fae8790e9c1ff2c' 
  AND token = 'Pkgrde+t/isYaQkvcWRrSJhQhBskVltHqQp5gnoaW10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}