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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0da4e6dc2325f1aa826870013197e9ed6573cb220d5798d11d8778be914f0129' 
  AND token = 'sA8NvF7IXg5X2h4LiFPhCzAOIcdg+Q5u1nJ43lMHLdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}