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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '748189c9c374f23912883fbadcd522851d57c6627a1f5d98430a85e072275412' 
  AND token = 'ccskXW516DC3Lt255bF0naPIMWepBC7OVHnl/yBonyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}