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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd87321705bbb99e537bbacf1b50408be2eaa72be14779f0a1d7ff1295f0546c1' 
  AND token = '0Y9zTLwIEPd1kI+EosFLz4N3Ol2MJ48nu9qY/NDIXGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}