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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f3c51341fceef08c8223c961f53ba0acac44bd8795c31f0b4412a1feb16c341' 
  AND token = 'peyxk3kQyPNwuqTOjWDEItyrAAT3r4LSyNhdTO+fjUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}