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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd72e0ade8faa8b941f04e9b25fbb10f10e2d2e750d1a4d9c87025f98aea93100' 
  AND token = 'jLEaC8edQpdTnlt131vYf9Wf5SGUr+sPUgogLlqbfSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}