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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '139422ac0c355959a4d7725195c30003e56c75195d23e5f33a091921f545d41a' 
  AND token = 't3AmdljfEkNaF2cHk7jBZDtRntI5JpnXfLbnDi0RTM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}