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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '018a3cea8aac8d3b8aec46993d3fab25081db9615fa4281fe88b1ed8d4c3fa00' 
  AND token = '0u2d/G6gnOpLeC/oxwvDOuktP9hy6dDN+KZAQLYZLmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}