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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88224031cac215366a104a5d4cc074e5152c1c862cf3cde6ad4433067d0683fb' 
  AND token = 'KrlYG0oDBkAARP7HfE55i9MK5VV2akUZhhVhrxtYHtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}