SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c00ff14b3a720d95ea1125b76db18ff24a2d99b4427ac7ec2c29f71146f8146' 
  AND token = '2RITkxT75Jj3t9qhMVu1EvybyYEaEuCQ5rKnj4b61GY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}