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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46f730f651ac52d9ea32130d35d38acff298768e90321cd5a88d04b8401fc0fe' 
  AND token = '1QQDtlhZZyG+EiXOG1RaSGSDzRgb7dP/96WpNbUNn98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}