SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5cc855c40666008acc88e63b85aa2568674c875cd562d32fe2ecbce019e3b14' 
  AND token = 'VPXLg8S1d6hTcaR3MhOiGwaN/8OMcFX58HtSdUaIjdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}