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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0918e6ed2fee60c92b136e7ecef0234be701087fcf7854bad56a3fa6aeec6c02' 
  AND token = 'd6U0BoyWAhl3+gNeRCEgZIh4gbqoR3hpQRG/wOHNxnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}