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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d60d7e8a7b89e02301194d2e12f251bc74281caf3903e2c1da9e4c3943e711c' 
  AND token = 'xH9yxuPN+6JYtM37mle075eAsUYAD1LUZK3G27XuIWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}