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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78222aa3549552810fb1a9f43d3fc99ebd4191c4318921b11071f614b8e7d4ee' 
  AND token = 'eMFw2ec7aAKMjWLZYJ5XEOSbsT9zfkJzQUT2c14hL0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}