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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e2d3f99fe04e4af2127d2c89e7923594538ce778c4caeace209766a3e6d0a5b' 
  AND token = '0cYzSSTbaeosXbqvKGNWJEeVEnMcEyKtvv0G2fCs1Oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}