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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4167822ead3d9b11243510de9a41f099e7b27062a5feb9ee394a902b7e46cae' 
  AND token = 'mJUVOIAv1EJ0fNyDOMKUgkROL82JG9V0j0EDCMNMa5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}