SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '778756c24db2c6d2a3780e11b5ec99c6e8f811b3fa11bf2e1d92666919a8240a' 
  AND token = 'NkWVtSNFUt9xW1iQG2qAEQouebwmlX3WvVUI7Q1thhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}