SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3303bdc07f3cd754f6f0fa8405c6694ffc89fd17de901663797f377bd8c11eb3' 
  AND token = 'a3tGTHPXGlrkU3cNSYJ5UwkpDs4ttPlIrMEVAC7PqZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}