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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c44ab9f1267d2045296698efbdeb529ee2469b1305a4d2f04f73aa2bb6a0155' 
  AND token = 'OdHuMn6ls1I35YY5q1VRFUIzO0SHuFAcjNuc9PdJJM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}