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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b1b9eb3abcb310cd350365e7d4e93c8d388fc9acedb493ed1541738cec0ff57' 
  AND token = 'EnPaskWY462exWJwdtg2Wl2bUWaE01ExTlTUFDStAqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}