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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07434926ae72ac25577a582efefbc7a5dca02153ab9a4c73edb01f2635f36144' 
  AND token = 'lUKN9Qfx9qa1JOSg1osKwpOAn8wK6gTh7ebNaxpRpJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}