SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f8a5ef626e796cddbde94a96e3d59a53e1332955b9467cdbb766a30ed809755' 
  AND token = 'FkC3IO7pxTiS6/NfX5IGjw8YhrX8iDCDY/ZeVNbeij4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}