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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9059a99f56cecb82b9a4fb2828abc0f11da176ad8c9e25ce2bc870aa809dd86' 
  AND token = 'JF/eExUYDVaLM9ggM8C1pfEH1sxX/PwJJj4Ur8JC47g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}