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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d8063833f36e3b25f887ae7a04181ecf3e7ee6cae070dd5d839df184d5dc484' 
  AND token = 'UyQ/7ou6bV820SSd4HNINFSUM0yWlOiFDufYQQjsG7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}