SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a597c1c681eda7ffaff173f9a849da69c20196824dc0f013472623dfc3303eb' 
  AND token = 'VGxlRpAbF7uMjsK2wKSFeD2APL3PQ7vucZu3DZZdGlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}