SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '314f625cc4f4e45b4e858a1d1489f313a9abc2d79cf904ce343aabbc9b0a6502' 
  AND token = 'A5tC2OcgCyVzdoWjzi6IfiwHAskzW9AAKcmLbVmlZOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}