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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53e15f5c38855de42ab798df54be3657eded95557b03d061ed9d0608a354ca5d' 
  AND token = 'mMCxvt0K60RhUdsz8ZquMfwFr6kX7qASNv4HtS1/1b8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}