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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bd003940da75d0839ad18edfa0935696312d0b84511576269421503260ed0f8' 
  AND token = 'm41W9JOtkmYPM8U0vUfkeaCAJ5XFuXKYxKTz4r2XrOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}