SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a9c71aa107ff1ec818833ae8ab71643d7f8d3a5148f42aa3525feb12d6f593e' 
  AND token = 'Y+mEB6K6IsLEiTJiBvSBnV6QMv3ZJW/sE3HcyIyTvuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}