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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bdf78fd939fa6ddbdb85e6c29acb2f455cb7f872a00d60ecb8fdaa77695da2a5' 
  AND token = '8DYgFzjMGkqmtFrPmcNvEeMtT4mwnlz5AwOCJgxTsGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}