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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '583146221933c8d253a28e60d88a64b6372d90ff93086cc5766f1102e596cfc2' 
  AND token = 'Jh8j9wzsK5OS2q43mLQkfzBMIXakOZNN3bpETZoJ0Zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}