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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e64b417cf9a250aa214c1077395cafcb37db48c830e8819831a6500e8cbe81e4' 
  AND token = '4S76FXo7r1S5moPzB0W/VvfCd9RBS5hsz4uiiLYq95w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}