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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '529c47a4b43df42d071a8fb0908336de4cab4402c6f258d0c5831a3022e00d76' 
  AND token = 'v1ZlqMxT+FoX+oPHw1+VEPQmIoqKm2oUVXctm0hrpPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}