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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64ad56073f95ee8084f899fa8f24e3fd35715621a19da8fd3de38ac13ee0f200' 
  AND token = 'xMh+4ND971Hil5l72aQq8mzHfnrN2wrDBvEYc0AWM5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}