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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '350f85643302b1c5cb0ca944761443de805361c401f8b9105cf637f5b6e2c854' 
  AND token = 'IooTs8sIg4lV8ub4E0VR2ceSqZTl1NF3w1xl9vaNkP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}