SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58ba61d0fe552ebed6040ff88dd559b3b143b7452de00a2551624284d9de66e2' 
  AND token = '9YS0sFJFSrZ2TF7eEsDg1XhMyGkz6d1xPbkVRO4kU4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}