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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adb758af70a5aa074eb00220c92b288c5c0904f9c256e37943e1172f9b6b8351' 
  AND token = 'qnVobADzxFlVkOVqAsgB8reCS2u2H+ahsLDxtK94jq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}