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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12eca3ddfd09ab6c89307af498ceb77c67f204afbb0bce0244e408a313670357' 
  AND token = '6kJwUmAPxDyupzwOY0d2Y+hw/gtQK5f0nR4y7nhNYsY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}