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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0e44dc47d58302a4cf9e2b68bf989f5ee0f157d7cede262888bca50efafbe8e' 
  AND token = 'XJDJ2t63d+lgkUXrvj4CnUgi7N1MLwo4KyT0qTvMQco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}