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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05ae6bbf0e1c7f1f9a1433992691f3f03a3dc38833e01d80e53a7681904e22bd' 
  AND token = 'ORjwEQ/jC6DOwF3CmQkFbYP7jkNjc3VEXMa5TjIYvCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}