SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ef4aea39e2ed018ea3ea239e93a8143aa22de6508bb5b928975663532580e27' 
  AND token = 'lul/o1vYAX9ntL1+kkXC6N0D8XFqrHHXDlSiltmriEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}