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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f772206e16d396a77cc0f8498634389d3f908f66b58c9b648659e6a40e9c457' 
  AND token = 'nwVJ1zeC3XEZfyhD2bQx16BYO7oYE9Ze2dF+rBLXXko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}