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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '369325f8cd980f48df523a1a26bb39446fda875d0693f5e67fb4b2bd1305f1e1' 
  AND token = 'pGae+3LaYT/HYUCPVPXPXf2Xz7wtXXwnT6tOgitsQfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}