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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c5f0bc152c9b653b5ae1d1464726cc1a6951be7c3a72bdcf5e42197e1003492' 
  AND token = '8xhxRHPdqkzR9yl0o02Ie9KTuFAwpuZsC/3du+pMZ28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}