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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08f5a9fff441c9827db895b93a649ba1897e8ecbf6705dc3e9c960f15e980d36' 
  AND token = '2T+WoT0NLqbYb6NF4tN244YxasvZFxnz/V/lPxFFR34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}