SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3675ec259017b6c5b589060cc04598ba6d6fba0213cd44063ae3ef87eeab78f5' 
  AND token = 'VZGQiOaEdbAZtx1IHid2uZYrFMikOXBJfUW8+juftO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}