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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e3c6365e1e14d3bdd4f50cda8819c2a6ef943d96757b10f91fddb45df52a040' 
  AND token = 'esBM2dSGsqEVwoscBcX0rKVwylXWmAlVuZuTcKE4D4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}