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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52e0b8c01ecc93b0b3ea38e3aec25e0e45ce89f908d22d45ba43bdfe343ac481' 
  AND token = 'FE5ut1gdXhGwnpaJ6PT6AvXJUewvzYrTJUK3QGqiqjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}